"Nucleic Acids And Precision Therapies For Neuroprotection

Neurodegenerative disorders are rising worldwide yet most approved drugs merely temper symptoms. Nucleic Acids and Precision Therapies for Neuroprotection addresses this therapeutic shortfall directly tracing how antisense oligonucleotides RNA interference agents m RNA platforms aptamers and CRISPR-class editors are redefining what treatable means for Alzheimer’s Parkinson’s ALS Huntington’s disease and Multiple Sclerosis. Rather than cataloguing modalities in isolation the book lays out an end-to-end translational roadmap from target identification and sequence optimisation to blood–brain barrier traversal immunogenicity management scalable manufacturing and ethical oversight. Delivery science (including viral nanoparticle and hybrid vectors) AI-enabled biomarker discovery adaptive trial architectures and shifting global regulatory frameworks are viewed as interlocking elements of a single development pathway. By aligning disparate scientific dialects into a shared practice-oriented language Nucleic Acids and Precision Therapies for Neuroprotection offers what the field currently lacks: a cohesive guide for moving nucleic acid therapeutics from concept to clinic with precision. Researchers clinicians regulators and industry teams will find pragmatic frameworks comparative tables and decision points that shorten the path between mechanistic insight and patient impact without sacrificing rigour or transparency. KEY FEATURES: Integrates molecular design delivery engineering clinical trial strategy and regulatory science into one end-to-end translational workflow for nucleic acid therapeutics in neurology Delivers disease-specific playbooks (AD PD ALS HD MS) that map genotype/phenotype data to actionable targets modality selection and delivery routes Embeds AI/ML-driven biomarker discovery patient stratification and manufacturability analytics alongside ethical access and cost considerations