Itch Mechanisms And Treatment

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch pain itch and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed direct-line communication system from the skin to the brain.Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis neuropathic itch cutaneous t-cells lymphomas and systemic diseases such as kidney and liver disease and cancer.Composed of contributions from distinguished researchers around the world the book explores topics such as:Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms the book is a compendium of the most current research on itch its prevalence in society and the problems associated with treatment. |Itch Mechanisms and Treatment